In 2025, Beto ran for Mayor of San Antonio, his first run for public office, finishing third in a field of 27 and outpacing every sitting council member. He launched at a neighborhood ice house and hosted over 60 community events and town halls across the South Side, West Side, Northwest Side, North Side, and East Side, knocking on thousands of doors to build Plan 210, a platform focused on public safety, infrastructure, workforce, and housing. Backed by leaders like former Mayor Nelson Wolff and former Rep. Joe Farias, and powered by more grassroots support than any candidate in the race, Beto ran a campaign rooted in one belief: San Antonio’s future belongs to the people who call it home.